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Mitochondrial thiol oxidase Erv1: both shuttle cysteine residues are required for its function with distinct roles

Erv1 (essential for respiration and viability 1), is an essential component of the MIA (mitochondrial import and assembly) pathway, playing an important role in the oxidative folding of mitochondrial intermembrane space proteins. In the MIA pathway, Mia40, a thiol oxidoreductase with a CPC motif at...

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Detalles Bibliográficos
Autores principales: Ang, Swee Kim, Zhang, Mengqi, Lodi, Tiziana, Lu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019985/
https://www.ncbi.nlm.nih.gov/pubmed/24625320
http://dx.doi.org/10.1042/BJ20131540