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Lentivirus-Mediated Nox4 shRNA Invasion and Angiogenesis and Enhances Radiosensitivity in Human Glioblastoma

Radioresistance remains a significant therapeutic obstacle in glioblastoma. Reactive oxygen species (ROS) are associated with multiple cellular functions such as cell proliferation and apoptosis. Nox4 NADPH oxidase is abundantly expressed and has proven to be a major source of ROS production in glio...

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Detalles Bibliográficos
Autores principales: Li, Yongsheng, Han, Na, Yin, Tiejun, Huang, Lulu, Liu, Shunfang, Liu, Dongbo, Xie, Cuihong, Zhang, Mengxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020159/
https://www.ncbi.nlm.nih.gov/pubmed/24868315
http://dx.doi.org/10.1155/2014/581732