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Targeting mRNA for Alzheimer's and Related Dementias

Brain deposition of the amyloid beta-protein (Aβ) and tau are characteristic features in Alzheimer's disease (AD). Mutations in the Aβ precursor protein (APP) and a protease involved in Aβ production from APP strongly argue for a pathogenic role of Aβ in AD, while mutations in tau are associate...

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Detalles Bibliográficos
Autor principal: Wolfe, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020195/
https://www.ncbi.nlm.nih.gov/pubmed/24876993
http://dx.doi.org/10.1155/2014/757549