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Targeting mRNA for Alzheimer's and Related Dementias
Brain deposition of the amyloid beta-protein (Aβ) and tau are characteristic features in Alzheimer's disease (AD). Mutations in the Aβ precursor protein (APP) and a protease involved in Aβ production from APP strongly argue for a pathogenic role of Aβ in AD, while mutations in tau are associate...
Autor principal: | Wolfe, Michael S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020195/ https://www.ncbi.nlm.nih.gov/pubmed/24876993 http://dx.doi.org/10.1155/2014/757549 |
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