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Amarogentin, a Secoiridoid Glycoside, Abrogates Platelet Activation through PLCγ2-PKC and MAPK Pathways

Amarogentin, an active principle of Gentiana lutea, possess antitumorigenic, antidiabetic, and antioxidative properties. Activation of platelets is associated with intravascular thrombosis and cardiovascular diseases. The present study examined the effects of amarogentin on platelet activation. Amar...

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Detalles Bibliográficos
Autores principales: Yen, Ting-Lin, Lu, Wan-Jung, Lien, Li-Ming, Thomas, Philip Aloysius, Lee, Tzu-Yin, Chiu, Hou-Chang, Sheu, Joen-Rong, Lin, Kuan-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020542/
https://www.ncbi.nlm.nih.gov/pubmed/24868545
http://dx.doi.org/10.1155/2014/728019