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Open-label Bendamustine Monotherapy for Pediatric Patients With Relapsed or Refractory Acute Leukemia: Efficacy and Tolerability

This open-label, single-arm, phase I/II, dose-escalation study was designed to determine the recommended phase II dose (RP2D), pharmacokinetics, tolerability, and efficacy of bendamustine in pediatric patients (age ranging from 1 to 20 y) with histologically proven relapsed/refractory acute lymphobl...

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Detalles Bibliográficos
Autores principales: Fraser, Chris, Brown, Patrick, Megason, Gail, Ahn, Hyo Seop, Cho, Bin, Kirov, Ivan, Frankel, Lawrence, Aplenc, Richard, Bensen-Kennedy, Debra, Munteanu, Mihaela, Weaver, Jennifer, Harker-Murray, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020582/
https://www.ncbi.nlm.nih.gov/pubmed/24072240
http://dx.doi.org/10.1097/MPH.0000000000000021