Cargando…

Side-Chain Oxysterols Modulate Cholesterol Accessibility through Membrane Remodeling

[Image: see text] Side-chain oxysterols, such as 25-hydroxycholesterol (25-HC), are key regulators of cholesterol homeostasis. New evidence suggests that the alteration of membrane structure by 25-HC contributes to its regulatory effects. We have examined the role of oxysterol membrane effects on ch...

Descripción completa

Detalles Bibliográficos
Autores principales: Bielska, Agata A., Olsen, Brett N., Gale, Sarah E., Mydock-McGrane, Laurel, Krishnan, Kathiresan, Baker, Nathan A., Schlesinger, Paul H., Covey, Douglas F., Ory, Daniel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020583/
https://www.ncbi.nlm.nih.gov/pubmed/24758724
http://dx.doi.org/10.1021/bi5000096