Sulfonylurea action re‐revisited

Sulfonylureas (SU), commonly used in the treatment of type 2 diabetes mellitus (T2DM), stimulate insulin secretion by inhibiting adenosine triphosphate (ATP)‐sensitive K(+) (K(ATP)) channels in pancreatic β‐cells. SU are now known to also activate cyclic adenosine monophosphate (cAMP) sensor Epac2 (...

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Detalles Bibliográficos
Autores principales: Seino, Susumu, Zhang, Chang‐Liang, Shibasaki, Tadao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020675/
https://www.ncbi.nlm.nih.gov/pubmed/24843406
http://dx.doi.org/10.1111/j.2040-1124.2010.00014.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020675/
https://www.ncbi.nlm.nih.gov/pubmed/24843406
http://dx.doi.org/10.1111/j.2040-1124.2010.00014.x

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