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Combination treatment of db/db mice with exendin‐4 and gastrin preserves β‐cell mass by stimulating β‐cell growth and differentiation

Aim/Introduction:  Preservation of β‐cell mass is crucial for maintaining long‐term glucose homeostasis. Therapies based on incretin and its mimetics are expected to achieve this goal through various biological functions, particularly the restoration of β‐cell mass. Here we tested the effects of gas...

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Detalles Bibliográficos
Autores principales: Tamaki, Motoyuki, Fujitani, Yoshio, Uchida, Toyoyoshi, Hirose, Takahisa, Kawamori, Ryuzo, Watada, Hirotaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020718/
https://www.ncbi.nlm.nih.gov/pubmed/24843429
http://dx.doi.org/10.1111/j.2040-1124.2010.00044.x