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SOCS1 Regulates the Immune Modulatory Properties of Mesenchymal Stem Cells by Inhibiting Nitric Oxide Production

Mesenchymal stem cells (MSCs) have been shown to be highly immunosuppressive and have been employed to treat various immune disorders. However, the mechanisms underlying the immunosuppressive capacity of MSCs are not fully understood. We found the suppressor of cytokine signaling 1 (SOCS1) was induc...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Dang, Rui-Jie, Li, Hong, Li, Ping, Yang, Yan-Mei, Guo, Xi-Min, Wang, Xiao-Yan, Fang, Nan-Zhu, Mao, Ning, Wen, Ning, Jiang, Xiao-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020773/
https://www.ncbi.nlm.nih.gov/pubmed/24826993
http://dx.doi.org/10.1371/journal.pone.0097256