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Genetic Signature of Histiocytic Sarcoma Revealed by a Sleeping Beauty Transposon Genetic Screen in Mice

Histiocytic sarcoma is a rare, aggressive neoplasm that responds poorly to therapy. Histiocytic sarcoma is thought to arise from macrophage precursor cells via genetic changes that are largely undefined. To improve our understanding of the etiology of histiocytic sarcoma we conducted a forward genet...

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Detalles Bibliográficos
Autores principales: Been, Raha A., Linden, Michael A., Hager, Courtney J., DeCoursin, Krista J., Abrahante, Juan E., Landman, Sean R., Steinbach, Michael, Sarver, Aaron L., Largaespada, David A., Starr, Timothy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020815/
https://www.ncbi.nlm.nih.gov/pubmed/24827933
http://dx.doi.org/10.1371/journal.pone.0097280