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Broad T-Cell Receptor Repertoire in T-Lymphocytes Derived from Human Induced Pluripotent Stem Cells

Human induced pluripotent stem cells (hiPSCs) have enormous potential for the treatment of inherited and acquired disorders. Recently, antigen-specific T lymphocytes derived from hiPSCs have been reported. However, T lymphocyte populations with broad T cell receptor (TCR) diversity have not been gen...

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Detalles Bibliográficos
Autores principales: Chang, Chia-Wei, Lai, Yi-Shin, Lamb, Lawrence S., Townes, Tim M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020825/
https://www.ncbi.nlm.nih.gov/pubmed/24828440
http://dx.doi.org/10.1371/journal.pone.0097335