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Identification of Heparin-Binding EGF-Like Growth Factor (HB-EGF) as a Biomarker for Lysophosphatidic Acid Receptor Type 1 (LPA(1)) Activation in Human Breast and Prostate Cancers
Lysophosphatidic acid (LPA) is a natural bioactive lipid with growth factor-like functions due to activation of a series of six G protein-coupled receptors (LPA(1–6)). LPA receptor type 1 (LPA(1)) signaling influences the pathophysiology of many diseases including cancer, obesity, rheumatoid arthrit...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020852/ https://www.ncbi.nlm.nih.gov/pubmed/24828490 http://dx.doi.org/10.1371/journal.pone.0097771 |