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Identification of Heparin-Binding EGF-Like Growth Factor (HB-EGF) as a Biomarker for Lysophosphatidic Acid Receptor Type 1 (LPA(1)) Activation in Human Breast and Prostate Cancers

Lysophosphatidic acid (LPA) is a natural bioactive lipid with growth factor-like functions due to activation of a series of six G protein-coupled receptors (LPA(1–6)). LPA receptor type 1 (LPA(1)) signaling influences the pathophysiology of many diseases including cancer, obesity, rheumatoid arthrit...

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Detalles Bibliográficos
Autores principales: David, Marion, Sahay, Debashish, Mege, Florence, Descotes, Françoise, Leblanc, Raphaël, Ribeiro, Johnny, Clézardin, Philippe, Peyruchaud, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020852/
https://www.ncbi.nlm.nih.gov/pubmed/24828490
http://dx.doi.org/10.1371/journal.pone.0097771