Deep Intronic Mutation and Pseudo Exon Activation as a Novel Muscular Hypertrophy Modifier in Cattle

Myostatin is essential for proper regulation of myogenesis, and inactivation of Myostatin results in muscle hypertrophy. Here, we identified an unexpected mutation in the myostatin gene which is almost fixed in Blonde d'Aquitaine cattle. In skeletal muscle, the mutant allele was highly expresse...

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Detalles Bibliográficos
Autores principales: Bouyer, Claire, Forestier, Lionel, Renand, Gilles, Oulmouden, Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020855/
https://www.ncbi.nlm.nih.gov/pubmed/24827585
http://dx.doi.org/10.1371/journal.pone.0097399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020855/
https://www.ncbi.nlm.nih.gov/pubmed/24827585
http://dx.doi.org/10.1371/journal.pone.0097399

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