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Structure and Catalytic Regulatory Function of Ubiquitin Specific Protease 11 N-Terminal and Ubiquitin-like Domains

[Image: see text] The ubiquitin specific protease 11 (USP11) is implicated in DNA repair, viral RNA replication, and TGFβ signaling. We report the first characterization of the USP11 domain architecture and its role in regulating the enzymatic activity. USP11 consists of an N-terminal “domain presen...

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Detalles Bibliográficos
Autores principales: Harper, Stephen, Gratton, Hayley E., Cornaciu, Irina, Oberer, Monika, Scott, David J., Emsley, Jonas, Dreveny, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020902/
https://www.ncbi.nlm.nih.gov/pubmed/24724799
http://dx.doi.org/10.1021/bi500116x