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Antitumor activity of sorafenib and imatinib in a patient with thymic carcinoma harboring c-KIT exon 13 missense mutation K642E

We report the case of a man with an advanced nonkeratinizing squamous cell thymic carcinoma harboring c-KIT exon 13 missense mutation K642E. This aberration is rare and has never been described previously in patients with thymic cancers. It has been found in a small number of cases of gastrointestin...

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Detalles Bibliográficos
Autores principales: Catania, Chiara, Conforti, Fabio, Spitaleri, Gianluca, Barberis, Massimo, Preda, Lorenzo, Noberasco, Cristina, Lazzari, Chiara, Toffalorio, Francesca, de Marinis, Filippo, Manzotti, Michela, De Pas, Tommaso Martino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020909/
https://www.ncbi.nlm.nih.gov/pubmed/24855380
http://dx.doi.org/10.2147/OTT.S58902