Metformin induces an intracellular reductive state that protects oesophageal squamous cell carcinoma cells against cisplatin but not copper-bis(thiosemicarbazones)

BACKGROUND: Oesophageal squamous cell carcinoma (OSCC) is a highly aggressive carcinoma with a poor survival rate. One of the most commonly used chemotherapeutic drugs, cisplatin, displays varied and often poor efficacy in vivo. Therefore, alternative, cost-effective and more efficacious treatments...

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Detalles Bibliográficos
Autores principales: Damelin, Leonard Howard, Jivan, Rupal, Veale, Robin Bruce, Rousseau, Amanda Louise, Mavri-Damelin, Demetra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020916/
https://www.ncbi.nlm.nih.gov/pubmed/24886082
http://dx.doi.org/10.1186/1471-2407-14-314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020916/
https://www.ncbi.nlm.nih.gov/pubmed/24886082
http://dx.doi.org/10.1186/1471-2407-14-314

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