Cargando…

Tertiary-Amine Functionalized Polyplexes Enhanced Cellular Uptake and Prolonged Gene Expression

Ultrasound (US) has been found to facilitate the transport of DNA across cell membranes. However, the transfection efficiency is generally low, and the expression duration of the transfected gene is brief. In this study, a tertiary polycation, Poly(2-(dimethylamino) ethyl methacrylate) (PDMAEMA), wa...

Descripción completa

Detalles Bibliográficos
Autores principales: Lo, Chia-Wen, Chang, Yung, Lee, Jyun-Lin, Tsai, Wei-Bor, Chen, Wen-Shiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020921/
https://www.ncbi.nlm.nih.gov/pubmed/24827929
http://dx.doi.org/10.1371/journal.pone.0097627