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Tertiary-Amine Functionalized Polyplexes Enhanced Cellular Uptake and Prolonged Gene Expression
Ultrasound (US) has been found to facilitate the transport of DNA across cell membranes. However, the transfection efficiency is generally low, and the expression duration of the transfected gene is brief. In this study, a tertiary polycation, Poly(2-(dimethylamino) ethyl methacrylate) (PDMAEMA), wa...
Autores principales: | Lo, Chia-Wen, Chang, Yung, Lee, Jyun-Lin, Tsai, Wei-Bor, Chen, Wen-Shiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020921/ https://www.ncbi.nlm.nih.gov/pubmed/24827929 http://dx.doi.org/10.1371/journal.pone.0097627 |
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