Homeostatic Maintenance of Allele-Specific p16 Methylation in Cancer Cells Accompanied by Dynamic Focal Methylation and Hydroxymethylation

AIM: p16 Methylation frequently occurs in carcinogenesis. While it has been hypothesized that the p16 methylation states are dynamically maintained in cancer cells, direct evidence supporting this hypothesis has not been available until now. METHODS: A fusion cell model was established which reprogr...

Descripción completa

Detalles Bibliográficos
Autores principales: Qin, Sisi, Li, Qiang, Zhou, Jing, Liu, Zhao-jun, Su, Na, Wilson, James, Lu, Zhe-ming, Deng, Dajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020935/
https://www.ncbi.nlm.nih.gov/pubmed/24828678
http://dx.doi.org/10.1371/journal.pone.0097785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020935/
https://www.ncbi.nlm.nih.gov/pubmed/24828678
http://dx.doi.org/10.1371/journal.pone.0097785

Ejemplares similares