Reduced fibulin-2 contributes to loss of basement membrane integrity and skin blistering in mice lacking integrin α3β1 in the epidermis

Deficient epidermal adhesion is a hallmark of blistering skin disorders and chronic wounds, implicating integrins as potential therapeutic targets. Integrin α3β1, a major receptor in epidermis for adhesion to laminin-332, plays critical roles in basement membrane organization during skin development...

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Detalles Bibliográficos
Autores principales: Longmate, Whitney M., Monichan, Ruby, Chu, Mon-Li, Tsuda, Takeshi, Mahoney, My G., DiPersio, C. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020984/
https://www.ncbi.nlm.nih.gov/pubmed/24390135
http://dx.doi.org/10.1038/jid.2014.10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020984/
https://www.ncbi.nlm.nih.gov/pubmed/24390135
http://dx.doi.org/10.1038/jid.2014.10

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