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Circulating cell-free methylated DNA and lactate dehydrogenase release in colorectal cancer

BACKGROUND: Hypermethylation of DNA is an epigenetic alteration commonly found in colorectal cancer (CRC) and can also be detected in blood samples of cancer patients. Methylation of the genes helicase-like transcription factor (HLTF) and hyperplastic polyposis 1 (HPP1) have been proposed as prognos...

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Detalles Bibliográficos
Autores principales: Philipp, Alexander B, Nagel, Dorothea, Stieber, Petra, Lamerz, Rolf, Thalhammer, Isabel, Herbst, Andreas, Kolligs, Frank T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021086/
https://www.ncbi.nlm.nih.gov/pubmed/24708595
http://dx.doi.org/10.1186/1471-2407-14-245