Adaptable probabilistic mapping of short reads using position specific scoring matrices

BACKGROUND: Modern DNA sequencing methods produce vast amounts of data that often requires mapping to a reference genome. Most existing programs use the number of mismatches between the read and the genome as a measure of quality. This approach is without a statistical foundation and can for some da...

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Detalles Bibliográficos
Autores principales: Kerpedjiev, Peter, Frellsen, Jes, Lindgreen, Stinus, Krogh, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021105/
https://www.ncbi.nlm.nih.gov/pubmed/24717095
http://dx.doi.org/10.1186/1471-2105-15-100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021105/
https://www.ncbi.nlm.nih.gov/pubmed/24717095
http://dx.doi.org/10.1186/1471-2105-15-100

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