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Adaptable probabilistic mapping of short reads using position specific scoring matrices
BACKGROUND: Modern DNA sequencing methods produce vast amounts of data that often requires mapping to a reference genome. Most existing programs use the number of mismatches between the read and the genome as a measure of quality. This approach is without a statistical foundation and can for some da...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021105/ https://www.ncbi.nlm.nih.gov/pubmed/24717095 http://dx.doi.org/10.1186/1471-2105-15-100 |