Allosteric and Biased G Protein-Coupled Receptor Signaling Regulation: Potentials for New Therapeutics

G protein-coupled receptors (GPCRs) are seven-transmembrane proteins that participate in many aspects of the endocrine function and are important targets for drug development. They transduce signals mainly, but not exclusively, via hetero-trimeric G proteins, leading to a diversity of intracellular...

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Detalles Bibliográficos
Autores principales: Khoury, Etienne, Clément, Stéphanie, Laporte, Stéphane A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021147/
https://www.ncbi.nlm.nih.gov/pubmed/24847311
http://dx.doi.org/10.3389/fendo.2014.00068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021147/
https://www.ncbi.nlm.nih.gov/pubmed/24847311
http://dx.doi.org/10.3389/fendo.2014.00068

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