Microwave irradiation: synthesis and characterization of α-ketoamide and bis (α-ketoamide) derivatives via the ring opening of N-acetylisatin

BACKGROUND: The carbonyl group at position 2 of N-acetylisatin behaves as an amide which is more susceptible to nucleophilic attack via ring-opening in the presence of nucleophiles. Because of this behavior, in the present work we describe the microwave synthesis of a series of α-ketoamide and bis-(...

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Detalles Bibliográficos
Autores principales: El-Faham, Ayman, Khattab, Sherine N, Ghabbour, Hazem A, Fun, Hoong-Kun, H Siddiqui, M Rafiq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021159/
https://www.ncbi.nlm.nih.gov/pubmed/24839460
http://dx.doi.org/10.1186/1752-153X-8-27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021159/
https://www.ncbi.nlm.nih.gov/pubmed/24839460
http://dx.doi.org/10.1186/1752-153X-8-27

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