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Ubiquitin ligase A20 regulates p53 protein in human colon epithelial cells
BACKGROUND: Intestinal polyps may further develop into colon cancer; the pathogenesis is not clear. The p53 gene is an important anti-cancer gene in the body, which is suppressed in cancer. The ubiquitin E3 ligase A20 (A20) plays a role in regulating the activities of epithelial cells. This study wa...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021182/ https://www.ncbi.nlm.nih.gov/pubmed/24099634 http://dx.doi.org/10.1186/1423-0127-20-74 |