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Repositioning: the fast track to new anti-malarial medicines?

BACKGROUND: Repositioning of existing drugs has been suggested as a fast track for developing new anti-malarial agents. The compound libraries of GlaxoSmithKline (GSK), Pfizer and AstraZeneca (AZ) comprising drugs that have undergone clinical studies in other therapeutic areas, but not achieved appr...

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Detalles Bibliográficos
Autores principales: Lotharius, Julie, Gamo-Benito, Francisco Javier, Angulo-Barturen, Iñigo, Clark, Julie, Connelly, Michele, Ferrer-Bazaga, Santiago, Parkinson, Tanya, Viswanath, Pavithra, Bandodkar, Balachandra, Rautela, Nikhil, Bharath, Sowmya, Duffy, Sandra, Avery, Vicky M, Möhrle, Jörg J, Guy, R Kiplin, Wells, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021201/
https://www.ncbi.nlm.nih.gov/pubmed/24731288
http://dx.doi.org/10.1186/1475-2875-13-143