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Opposing microtubule motors control motility, morphology and cargo segregation during ER-to-Golgi transport

We recently demonstrated that dynein and kinesin motors drive multiple aspects of endosomal function in mammalian cells. These functions include driving motility, maintaining morphology (notably through providing longitudinal tension to support vesicle fission), and driving cargo sorting. Microtubul...

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Detalles Bibliográficos
Autores principales: Brown, Anna K., Hunt, Sylvie D., Stephens, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021352/
https://www.ncbi.nlm.nih.gov/pubmed/24705013
http://dx.doi.org/10.1242/bio.20147633