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MicroRNA-155 as an inducer of apoptosis and cell differentiation in Acute Myeloid Leukaemia

BACKGROUND: Acute myeloid leukaemia (AML) is characterised by the halt in maturation of myeloid progenitor cells, combined with uncontrolled proliferation and abnormal survival, leading to the accumulation of immature blasts. In many subtypes of AML the underlying causative genetic insults are not f...

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Detalles Bibliográficos
Autores principales: Palma, Catalina A, Al Sheikha, Dima, Lim, Teck Khai, Bryant, Adam, Vu, Thi Thanh, Jayaswal, Vivek, Ma, David D F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021368/
https://www.ncbi.nlm.nih.gov/pubmed/24708856
http://dx.doi.org/10.1186/1476-4598-13-79