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Increased genetic diversity of ADME genes in African Americans compared with their putative ancestral source populations and implications for Pharmacogenomics

BACKGROUND: African Americans have been treated as a representative population for African ancestry for many purposes, including pharmacogenomic studies. However, the contribution of European ancestry is expected to result in considerable differences in the genetic architecture of African American i...

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Detalles Bibliográficos
Autores principales: Li, Jing, Lao, Xingzhen, Zhang, Chao, Tian, Lei, Lu, Dongsheng, Xu, Shuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021503/
https://www.ncbi.nlm.nih.gov/pubmed/24884825
http://dx.doi.org/10.1186/1471-2156-15-52