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Hanging drop cultures of human testis and testis cancer samples: a model used to investigate activin treatment effects in a preserved niche
BACKGROUND: Testicular germ cell tumours of young adults, seminoma or non-seminomas, are preceded by a pre-invasive precursor, carcinoma in situ (CIS), understood to arise through differentiation arrest of embryonic germ cells. Knowledge about the malignant transformation of germ cells is currently...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021512/ https://www.ncbi.nlm.nih.gov/pubmed/24781282 http://dx.doi.org/10.1038/bjc.2014.160 |