Erroneous identification of APOBEC3-edited chromosomal DNA in cancer genomics

BACKGROUND: The revolution in cancer genomics shows that the dominant mutations are CG->TA transitions. The sources of these mutations are probably two host cell cytidine deaminases APOBEC3A and APOBEC3B. The former in particular can access nuclear DNA and monotonously introduce phenomenal number...

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Detalles Bibliográficos
Autores principales: Suspène, R, Caval, V, Henry, M, Bouzidi, M S, Wain-Hobson, S, Vartanian, J-P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021520/
https://www.ncbi.nlm.nih.gov/pubmed/24691422
http://dx.doi.org/10.1038/bjc.2014.176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021520/
https://www.ncbi.nlm.nih.gov/pubmed/24691422
http://dx.doi.org/10.1038/bjc.2014.176

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