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Multipoint targeting of the PI3K/mTOR pathway in mesothelioma

BACKGROUND: Mesothelioma is a notoriously chemotherapy-resistant neoplasm, as is evident in the dismal overall survival for patients with those of asbestos-associated disease. We previously demonstrated co-activation of multiple receptor tyrosine kinases (RTKs), including epidermal growth factor rec...

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Detalles Bibliográficos
Autores principales: Zhou, S, Liu, L, Li, H, Eilers, G, Kuang, Y, Shi, S, Yan, Z, Li, X, Corson, J M, Meng, F, Zhou, H, Sheng, Q, Fletcher, J A, Ou, W-B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021537/
https://www.ncbi.nlm.nih.gov/pubmed/24762959
http://dx.doi.org/10.1038/bjc.2014.220