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Targeting gallbladder cancer: oncolytic virotherapy with myxoma virus is enhanced by rapamycin in vitro and further improved by hyaluronan in vivo

BACKGROUND: Gallbladder carcinoma (GBC) is highly lethal, and effective treatment will require synergistic anti-tumor management. The study is aimed at investigating the oncolytic value of myxoma virus (MYXV) infection against GBC and optimizing MYXV oncolytic efficiency. METHODS: We examined the pe...

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Detalles Bibliográficos
Autores principales: Weng, Mingzhe, Gong, Wei, Ma, Mingzhe, Chu, Bingfeng, Qin, Yiyu, Zhang, Mingdi, Lun, Xueqing, McFadden, Grant, Forsyth, Peter, Yang, Yong, Quan, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021541/
https://www.ncbi.nlm.nih.gov/pubmed/24725816
http://dx.doi.org/10.1186/1476-4598-13-82