Autoinhibition of the Ron receptor tyrosine kinase by the juxtamembrane domain

BACKGROUND: The Ron receptor tyrosine kinase (RTK) has been implicated in the progression of a number of carcinomas, thus understanding the regulatory mechanisms governing its activity is of potential therapeutic significance. A critical role for the juxtamembrane domain in regulating RTK activity i...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xin, Yennawar, Neela, Hankey, Pamela A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021555/
https://www.ncbi.nlm.nih.gov/pubmed/24739671
http://dx.doi.org/10.1186/1478-811X-12-28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021555/
https://www.ncbi.nlm.nih.gov/pubmed/24739671
http://dx.doi.org/10.1186/1478-811X-12-28

Ejemplares similares