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A comparison of RNA-seq and exon arrays for whole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat

BACKGROUND: The past decade has seen an abundance of transcriptional profiling studies of preclinical models of persistent pain, predominantly employing microarray technology. In this study we directly compare exon microarrays to RNA-seq and investigate the ability of both platforms to detect differ...

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Detalles Bibliográficos
Autores principales: Perkins, James R, Antunes-Martins, Ana, Calvo, Margarita, Grist, John, Rust, Werner, Schmid, Ramona, Hildebrandt, Tobias, Kohl, Matthias, Orengo, Christine, McMahon, Stephen B, Bennett, David LH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021616/
https://www.ncbi.nlm.nih.gov/pubmed/24472155
http://dx.doi.org/10.1186/1744-8069-10-7