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Asynchronous transcriptional silencing of individual retroviral genomes in embryonic cells

BACKGROUND: Retroviral DNAs are profoundly silenced at the transcriptional level in embryonic cell types. The transcriptional profile of pluripotent stem cells has been demonstrated to be extremely heterogeneous from cell to cell, and how the silencing of retroviral DNAs is achieved is not yet well...

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Detalles Bibliográficos
Autores principales: Schlesinger, Sharon, Meshorer, Eran, Goff, Stephen P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021621/
https://www.ncbi.nlm.nih.gov/pubmed/24742368
http://dx.doi.org/10.1186/1742-4690-11-31