A multicenter study on Leigh syndrome: disease course and predictors of survival

BACKGROUND: Leigh syndrome is a progressive neurodegenerative disorder, associated with primary or secondary dysfunction of the mitochondrial oxidative phosphorylation. Despite the fact that Leigh syndrome is the most common phenotype of mitochondrial disorders in children, longitudinal natural hist...

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Detalles Bibliográficos
Autores principales: Sofou, Kalliopi, De Coo, Irenaeus F M, Isohanni, Pirjo, Ostergaard, Elsebet, Naess, Karin, De Meirleir, Linda, Tzoulis, Charalampos, Uusimaa, Johanna, De Angst, Isabell B, Lönnqvist, Tuula, Pihko, Helena, Mankinen, Katariina, Bindoff, Laurence A, Tulinius, Már, Darin, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021638/
https://www.ncbi.nlm.nih.gov/pubmed/24731534
http://dx.doi.org/10.1186/1750-1172-9-52

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021638/
https://www.ncbi.nlm.nih.gov/pubmed/24731534
http://dx.doi.org/10.1186/1750-1172-9-52

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