Cargando…

Development and Retranslational Validation of an In Vitro Model to Characterize Acute Infections in Large Human Joints

Bacterial infections can destroy cartilage integrity, resulting in osteoarthritis. Goal was to develop an in vitro model with in vivo validation of acute joint inflammation. Inflammation in cocultivated human synovial fibroblasts (SFB), chondrocytes (CHDR), and mononuclear cells (MNC) was successive...

Descripción completa

Detalles Bibliográficos
Autores principales: Pilz, Ingo H., Mehlhorn, Alexander, Dovi-Akue, David, Langenmair, Elia Raoul, Südkamp, Norbert P., Schmal, Hagen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021994/
https://www.ncbi.nlm.nih.gov/pubmed/24877141
http://dx.doi.org/10.1155/2014/848604