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Cisplatin-induced epigenetic activation of miR-34a sensitizes bladder cancer cells to chemotherapy

BACKGROUND: Accumulating evidence suggests a tumor suppressive role for miR-34a in human carcinogenesis. However, its precise biological role remains largely elusive. This study aimed to reveal the association of the miR-34a expression and its modulation of sensitivity to cisplatin in muscle-invasiv...

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Detalles Bibliográficos
Autores principales: Li, Heng, Yu, Gan, Shi, Runlin, Lang, Bin, Chen, Xianguo, Xia, Ding, Xiao, Haibing, Guo, Xiaolin, Guan, Wei, Ye, Zhangqun, Xiao, Wei, Xu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022035/
https://www.ncbi.nlm.nih.gov/pubmed/24423412
http://dx.doi.org/10.1186/1476-4598-13-8