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CD45RA(-)Foxp3(high) but not CD45RA(+)Foxp3(low) suppressive T regulatory cells increased in the peripheral circulation of patients with head and neck squamous cell carcinoma and correlated with tumor progression

BACKGROUND: T regulatory cells (Tregs) contribute to the progression of head and neck squamous cell carcinoma (HNSCC) by suppressing antitumor immunity. However, little is known regarding the functional heterogeneity of Tregs in HNSCC patients. METHODS: Using multicolor flow cytometry, the frequency...

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Detalles Bibliográficos
Autores principales: Sun, Wei, Li, Wei-Jin, Wu, Chang-You, Zhong, Hua, Wen, Wei-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022051/
https://www.ncbi.nlm.nih.gov/pubmed/24761979
http://dx.doi.org/10.1186/1756-9966-33-35