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CD45RA(-)Foxp3(high) but not CD45RA(+)Foxp3(low) suppressive T regulatory cells increased in the peripheral circulation of patients with head and neck squamous cell carcinoma and correlated with tumor progression
BACKGROUND: T regulatory cells (Tregs) contribute to the progression of head and neck squamous cell carcinoma (HNSCC) by suppressing antitumor immunity. However, little is known regarding the functional heterogeneity of Tregs in HNSCC patients. METHODS: Using multicolor flow cytometry, the frequency...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022051/ https://www.ncbi.nlm.nih.gov/pubmed/24761979 http://dx.doi.org/10.1186/1756-9966-33-35 |