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Platelet-derived growth factor regulates the secretion of extracellular vesicles by adipose mesenchymal stem cells and enhances their angiogenic potential

BACKGROUND: Several studies demonstrate the role of adipose mesenchymal stem cells (ASCs) in angiogenesis. The angiogenic mechanism has been ascribed to paracrine factors since these cells secrete a plenty of signal molecules and growth factors. Recently it has been suggested that besides soluble fa...

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Detalles Bibliográficos
Autores principales: Lopatina, Tatiana, Bruno, Stefania, Tetta, Ciro, Kalinina, Natalia, Porta, Massimo, Camussi, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022079/
https://www.ncbi.nlm.nih.gov/pubmed/24725987
http://dx.doi.org/10.1186/1478-811X-12-26