FGF-2 released from degenerating neurons exerts microglial-induced neuroprotection via FGFR3-ERK signaling pathway

BACKGROUND: The accumulation of activated microglia is a hallmark of various neurodegenerative diseases. Microglia may have both protective and toxic effects on neurons through the production of various soluble factors, such as chemokines. Indeed, various chemokines mediate the rapid and accurate mi...

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Detalles Bibliográficos
Autores principales: Noda, Mariko, Takii, Kento, Parajuli, Bijay, Kawanokuchi, Jun, Sonobe, Yoshifumi, Takeuchi, Hideyuki, Mizuno, Tetsuya, Suzumura, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022102/
https://www.ncbi.nlm.nih.gov/pubmed/24735639
http://dx.doi.org/10.1186/1742-2094-11-76

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022102/
https://www.ncbi.nlm.nih.gov/pubmed/24735639
http://dx.doi.org/10.1186/1742-2094-11-76

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