Desmoglein 3 acting as an upstream regulator of Rho GTPases, Rac-1/Cdc42 in the regulation of actin organisation and dynamics

Desmoglein 3 (Dsg3), a member of the desmoglein sub-family, serves as an adhesion molecule in desmosomes. Our previous study showed that overexpression of human Dsg3 in several epithelial lines induces formation of membrane protrusions, a phenotype suggestive of Rho GTPase activation. Here we examin...

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Detalles Bibliográficos
Autores principales: Man Tsang, Siu, Brown, Louise, Gadmor, Hanan, Gammon, Luke, Fortune, Farida, Wheeler, Ann, Wan, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022105/
https://www.ncbi.nlm.nih.gov/pubmed/22796473
http://dx.doi.org/10.1016/j.yexcr.2012.07.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022105/
https://www.ncbi.nlm.nih.gov/pubmed/22796473
http://dx.doi.org/10.1016/j.yexcr.2012.07.002

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