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Optimization of 3-D organotypic primary colonic cultures for organ-on-chip applications
BACKGROUND: New advances enable long-term organotypic culture of colonic epithelial stem cells that develop into structures known as colonoids. Colonoids represent a primary tissue source acting as a potential starting material for development of an in vitro model of the colon. Key features of colon...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022271/ https://www.ncbi.nlm.nih.gov/pubmed/24690469 http://dx.doi.org/10.1186/1754-1611-8-9 |