Cargando…

NQO1 gene rs1800566 variant is not associated with risk for multiple sclerosis

BACKGROUND: A possible role of oxidative stress in the pathogenesis of multiple sclerosis (MS) and in experimental autoimmune encephalomyelitis has been suggested. The detoxification enzyme NAD(P)H dehydrogenase, quinone 1 (NQO1) has been found up-regulated in MS lesions. A previous report described...

Descripción completa

Detalles Bibliográficos
Autores principales: Agúndez, José A G, García-Martín, Elena, Martínez, Carmen, Benito-León, Julián, Millán-Pascual, Jorge, Calleja, Patricia, Díaz-Sánchez, María, Pisa, Diana, Turpín-Fenoll, Laura, Alonso-Navarro, Hortensia, Ayuso-Peralta, Lucía, Torrecillas, Dolores, Plaza-Nieto, José Francisco, Jiménez-Jiménez, Félix Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022329/
https://www.ncbi.nlm.nih.gov/pubmed/24755231
http://dx.doi.org/10.1186/1471-2377-14-87