The risks and rewards of covariate adjustment in randomized trials: an assessment of 12 outcomes from 8 studies

BACKGROUND: Adjustment for prognostic covariates can lead to increased power in the analysis of randomized trials. However, adjusted analyses are not often performed in practice. METHODS: We used simulation to examine the impact of covariate adjustment on 12 outcomes from 8 studies across a range of...

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Detalles Bibliográficos
Autores principales: Kahan, Brennan C, Jairath, Vipul, Doré, Caroline J, Morris, Tim P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022337/
https://www.ncbi.nlm.nih.gov/pubmed/24755011
http://dx.doi.org/10.1186/1745-6215-15-139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022337/
https://www.ncbi.nlm.nih.gov/pubmed/24755011
http://dx.doi.org/10.1186/1745-6215-15-139

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