Cargando…

Up-regulation of heme oxygenase-1 after infarct initiation reduces mortality, infarct size and left ventricular remodeling: experimental evidence and proof of concept

BACKGROUND: Up-regulation of HO-1 by genetic manipulation or pharmacological pre-treatment has been reported to provide benefits in several animal models of myocardial infarction (MI). However, its efficacy following MI initiation (as in clinical reality) remains to be tested. Therefore, this study...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kusmic, Claudia, Barsanti, Cristina, Matteucci, Marco, Vesentini, Nicoletta, Pelosi, Gualtiero, Abraham, Nader G, L’Abbate, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022338/ https://www.ncbi.nlm.nih.gov/pubmed/24708733 http://dx.doi.org/10.1186/1479-5876-12-89

Ejemplares similares

Selection of reference genes in different myocardial regions of an in vivo ischemia/reperfusion rat model for normalization of antioxidant gene expression
por: Vesentini, Nicoletta, et al.
Publicado: (2012)

Percutaneous Cardiac Support during Myocardial Infarction Drastically Reduces Mortality: Perspectives from a Swine Model
por: Trivella, Maria Giovanna, et al.
Publicado: (2018)

Diabetes Impairs the Vascular Recruitment of Normal Stem Cells by Oxidant Damage, Reversed by Increases in pAMPK, Heme Oxygenase-1, and Adiponectin
por: Sambuceti, Gianmario, et al.
Publicado: (2009)

Effects of Heme Oxygenase-1 Upregulation on Blood Pressure and Cardiac Function in an Animal Model of Hypertensive Myocardial Infarction
por: Chen, Tian-meng, et al.
Publicado: (2013)

Effects of heme oxygenase-1 upregulation on isoproterenol-induced myocardial infarction
por: Eltobshy, Somaia A.G., et al.
Publicado: (2019)

Pharmacological and Clinical Significance of Heme Oxygenase-1
por: Stec, David E., et al.
Publicado: (2021)

The expression of myeloperoxidase in thrombi is associated with reduced heme oxygenase‐1 induction and worse left ventricular remodeling in patients with acute ST‐elevation myocardial infarction
por: Shi, Xibao, et al.
Publicado: (2021)

Impact of Obstructive Sleep Apnea Syndrome on Ventricular Remodeling after Acute Myocardial Infarction: A Proof-of-Concept Study
por: Bughin, François, et al.
Publicado: (2022)

Reduction of reperfusion-induced ventricular fibrillation and infarct size via heme oxygenase-1 overexpression in isolated mouse hearts
por: Bak, Istvan, et al.
Publicado: (2010)

Targeting Heme Oxygenase-1 in Cardiovascular and Kidney Disease
por: Drummond, Heather A., et al.
Publicado: (2019)

Targeting the Heme-Heme Oxygenase System to Prevent Severe Complications Following COVID-19 Infections
por: Wagener, Frank A. D. T. G., et al.
Publicado: (2020)

The Emerging Role of Heme Oxygenase and Its Metabolites in the Regulation of Cardiovascular Function
por: Stec, David E., et al.
Publicado: (2012)

Heme oxygenase-1 prevents heart against myocardial infarction by attenuating ischemic injury-induced cardiomyocytes senescence
por: Shan, Huitong, et al.
Publicado: (2018)

Heme Oxygenase-1 Deficiency
por: Renji, Soumya, et al.
Publicado: (2021)

Oxidative Stress and Heme Oxygenase-1 Regulated Human Mesenchymal Stem Cells Differentiation
por: Vanella, Luca, et al.
Publicado: (2012)

Applications of Deep Learning Algorithms to Ultrasound Imaging Analysis in Preclinical Studies on In Vivo Animals
por: De Rosa, Laura, et al.
Publicado: (2023)

Orthogonal decomposition of left ventricular remodeling in myocardial infarction
por: Zhang, Xingyu, et al.
Publicado: (2017)

Role of Heme Oxygenase as a Modulator of Heme-Mediated Pathways
por: Duvigneau, J. Catharina, et al.
Publicado: (2019)

Heme-heme oxygenase-2 reduces the atherosclerosis by preventing inflammation
por: Wang, Zhenzhen, et al.
Publicado: (2022)

OX-HDL: A Starring Role in Cardiorenal Syndrome and the Effects of Heme Oxygenase-1 Intervention
por: Peterson, Stephen J., et al.
Publicado: (2020)

Peroxynitrite-mediated inactivation of heme oxygenases
por: Kinobe, Robert, et al.
Publicado: (2004)

Heme oxygenase 1 regulates osteoclastogenesis
por: Zwerina, J, et al.
Publicado: (2005)

Curcumin and Heme Oxygenase: Neuroprotection and Beyond
por: Mhillaj, Emanuela, et al.
Publicado: (2019)

The non-canonical functions of the heme oxygenases
por: Vanella, Luca, et al.
Publicado: (2016)

Long-term prognosis of unheralded myocardial infarction vs chronic angina; role of sex and coronary atherosclerosis burden
por: Carpeggiani, Clara, et al.
Publicado: (2018)

Integrative Survival Response Evoked by Heme Oxygenase-1 and Heme Metabolites
por: Pae, Hyun-Ock, et al.
Publicado: (2008)

How Heme Oxygenase-1 Prevents Heme-Induced Cell Death
por: Lanceta, Lilibeth, et al.
Publicado: (2015)

A noncanonical heme oxygenase specific for the degradation of c-type heme
por: Li, Shuxin, et al.
Publicado: (2021)

Heme, Heme Oxygenase-1, Statins, and SARS-CoV-2
por: Stevenson, David K., et al.
Publicado: (2023)

Neutrophil roles in left ventricular remodeling following myocardial infarction
por: Ma, Yonggang, et al.
Publicado: (2013)

Therapeutic Roles of Heme Oxygenase-1 in Metabolic Diseases: Curcumin and Resveratrol Analogues as Possible Inducers of Heme Oxygenase-1
por: Son, Yong, et al.
Publicado: (2013)

Influence of infarct healing on left ventricular remodeling in patients with acute st-segment elevation myocardial infarction
por: Masci, Pier Giorgio, et al.
Publicado: (2011)

Relationship between location and size of myocardial infarction and their reciprocal influences on post-infarction left ventricular remodeling
por: Masci, Pier Giorgio, et al.
Publicado: (2011)

Selectins and Immune Cells in Acute Myocardial Infarction and Post-infarction Ventricular Remodeling: Pathophysiology and Novel Treatments
por: Weil, Brian R., et al.
Publicado: (2019)

Heme Oxygenase-1 Induction Improves Cardiac Function following Myocardial Ischemia by Reducing Oxidative Stress
por: Issan, Yossi, et al.
Publicado: (2014)

Positive Effects of Heme Oxygenase Upregulation on Adiposity and Vascular Dysfunction: Gene Targeting vs. Pharmacologic Therapy
por: Peterson, Stephen J., et al.
Publicado: (2019)

High fat diet enhances cardiac abnormalities in SHR rats: Protective role of heme oxygenase-adiponectin axis
por: Cao, Jian, et al.
Publicado: (2011)

Post-infarction cardiac remodeling—differential biomarkers for left atrial and left ventricular remodeling
por: Selejan, Simina-Ramona, et al.
Publicado: (2021)

Heme Oxygenase-1, Oxidation, Inflammation, and Atherosclerosis
por: Araujo, Jesus A., et al.
Publicado: (2012)

The Expression of Heme Oxygenase-1 Induced by Lansoprazole
por: Takagi, Tomohisa, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_jg55v33jub3t21qjcunmqicor8