MAP1B rescues LRRK2 mutant-mediated cytotoxicity

Leucine-rich repeat kinase 2 (LRRK2) mutations are the most common cause of dominant and sporadic Parkinson’s disease (PD), a common neurodegenerative disorder. Yeast-two-hybrid screening using human LRRK2 kinase domain as bait identified microtubule associated protein 1B (MAP1B) as a LRRK2 interact...

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Detalles Bibliográficos
Autores principales: Chan, Sharon L, Chua, Ling-Ling, Angeles, Dario C, Tan, Eng-King
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022373/
https://www.ncbi.nlm.nih.gov/pubmed/24754922
http://dx.doi.org/10.1186/1756-6606-7-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022373/
https://www.ncbi.nlm.nih.gov/pubmed/24754922
http://dx.doi.org/10.1186/1756-6606-7-29

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